MELTF

Across TCGA cell cohorts, MELTF protein abundance is significantly associated with the go_rna of many other GO terms, with 936 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MELTF-associated GO terms across cancer lineages are Negative regulation of receptor recycling, Protein import into peroxisome matrix, substrate release, and Nucleophagy. Each is linked with MELTF in more than 1 cancer types. Because this analysis shows association rather than direction, both MELTF-to-partner and partner-to-MELTF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of receptor recycling grouped by MELTF-low versus MELTF-high in BLOOD_Lymphoma.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MELTF→partner) and Y-score (partner→MELTF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of receptor recycling →	-0.188	-1.760	.005	.003	3	2
BLOOD_Lymphoma	Protein import into peroxisome matrix, substrate release →	-0.116	-1.722	.002	.003	3	1
BLOOD_Lymphoma	Nucleophagy →	-0.077	-1.357	.009	.009	3	1
BLOOD_Lymphoma	Positive regulation of T cell differentiation →	-0.140	-1.897	<.001	.002	3	1
BLOOD_Lymphoma	Positive regulation of lymphocyte differentiation →	-0.144	-2.002	<.001	<.001	3	1
BLOOD_Lymphoma	Regulation of T-helper 2 cell differentiation →	-0.311	-1.852	.004	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 936 associations by consensus.

Negative regulation of receptor recycling by MELTF expression — BLOOD_Lymphoma

Explore this box plot interactively →