MEIS2

Across TCGA patient cohorts, MEIS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,146 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MEIS2-associated proteins across cancer lineages are CACNA2D1, MAP1A, and LAMA4. Each is linked with MEIS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both MEIS2-to-partner and partner-to-MEIS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEIS2 versus CACNA2D1 in OV, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MEIS2→partner) and Y-score (partner→MEIS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CACNA2D1 →	+0.556	+1.264	.001	<.001	3	7
HNSC	MAP1A →	+0.702	+0.670	<.001	<.001	3	7
BRCA	LAMA4 →	+0.413	+0.478	<.001	<.001	3	6
OV	LAMB1 →	+0.653	+1.254	<.001	<.001	3	6
CCRCC	PRKG1 →	+0.519	+0.773	<.001	<.001	3	6
BRCA	RSU1 →	+0.342	+0.579	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,146 associations by consensus.

MEIS2 vs CACNA2D1 — OV

Explore this scatter interactively →