MEIOB

Across TCGA cell cohorts, MEIOB mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MEIOB-associated genes across cancer lineages are LILRA1, BPIFA1, and R3HDML. Each is linked with MEIOB in more than 1 cancer types. Because this analysis shows association rather than direction, both MEIOB-to-partner and partner-to-MEIOB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LILRA1 grouped by MEIOB-low versus MEIOB-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEIOB→partner) and Y-score (partner→MEIOB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LILRA1 →	+0.013	+4.095	.001	.009	3	1
LARGE_INTESTINE	BPIFA1 →	+0.178	+4.273	<.001	.006	3	1
BLOOD_Lymphoma	R3HDML →	+0.006	+5.209	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

LILRA1 by MEIOB expression — LARGE_INTESTINE

Explore this box plot interactively →