MEIKIN

Across TCGA patient cohorts, MEIKIN protein abundance is significantly associated with the RNA expression of many other genes, with 141 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MEIKIN-associated genes across cancer lineages are MCAT, SIX4, and NUMBL. Each is linked with MEIKIN in more than 1 cancer types. Because this analysis shows association rather than direction, both MEIKIN-to-partner and partner-to-MEIKIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEIKIN versus MCAT in CCRCC, with a Pearson correlation of -0.17.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEIKIN→partner) and Y-score (partner→MEIKIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MCAT →	-0.286	-0.280	.007	.001	3	1
CCRCC	SIX4 →	+0.250	+0.449	<.001	<.001	3	1
CCRCC	NUMBL →	+0.423	+0.358	<.001	.008	3	1
CCRCC	DENND3 →	+0.425	+0.350	<.001	<.001	3	1
CCRCC	KCNT1 →	+0.065	+0.415	.004	.001	3	1
CCRCC	SLC25A11 →	-0.348	-0.404	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 141 associations by consensus.

MEIKIN vs MCAT — CCRCC

Explore this scatter interactively →