Across TCGA patient cohorts, MEIG1 mutation is significantly associated with the RNA expression of many other genes, with 154 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MEIG1-associated genes across cancer lineages are LINC02448, MIR4698, and MERTK. Each is linked with MEIG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MEIG1-to-partner and partner-to-MEIG1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEIG1→partner) and Y-score (partner→MEIG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC02448 →	+0.225	+5.145	.002	.007	3	1
COAD	MIR4698 →	+0.539	+5.212	.002	.007	3	1
UCEC	MERTK →	+1.092	+3.191	<.001	.009	3	1
UCEC	NSD1 →	+0.604	+3.201	.005	.009	3	1
UCEC	GOLGA2 →	+0.703	+3.218	<.001	.009	3	1
UCEC	MUC7 →	+1.108	+3.632	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 154 associations by consensus.

Exploration

MEIG1 survival (RNA) · tumor vs normal (RNA) · all MEIG1 data types