MEI4

Across TCGA cell cohorts, MEI4 RNA expression is significantly associated with the go_rna of many other GO terms, with 439 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible MEI4-associated GO terms across cancer lineages are D-glucuronate catabolic process to D-xylulose 5-phosphate, D-glucuronate catabolic process, and Negative regulation of nuclear-transcribed mRNA poly(A) tail shortening. Each is linked with MEI4 in more than 3 cancer types. Because this analysis shows association rather than direction, both MEI4-to-partner and partner-to-MEI4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, D-glucuronate catabolic process to D-xylulose 5-phosphate grouped by MEI4-low versus MEI4-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEI4→partner) and Y-score (partner→MEI4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	D-glucuronate catabolic process to D-xylulose 5-phosphate →	-0.208	-0.091	<.001	.007	3	4
BONE	D-glucuronate catabolic process →	-0.208	-0.091	<.001	.007	3	4
BONE	Negative regulation of nuclear-transcribed mRNA poly(A) tail shortening →	+0.089	+0.089	<.001	.007	3	4
BONE	Glucuronate catabolic process →	-0.208	-0.091	<.001	.007	3	4
OVARY	Endoplasmic reticulum to cytosol transport →	+0.071	+0.085	.001	.006	3	4
OVARY	Retrograde protein transport, ER to cytosol →	+0.071	+0.085	.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 439 associations by consensus.

D-glucuronate catabolic process to D-xylulose 5-phosphate by MEI4 expression — BONE

Explore this box plot interactively →