MEI1

Across TCGA patient cohorts, MEI1 mutation is significantly associated with the RNA expression of many other genes, with 3,995 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MEI1-associated genes across cancer lineages are SNORA1B, ALDH7A1P2, and C14orf119. Each is linked with MEI1 in more than 2 cancer types. Because this analysis shows association rather than direction, both MEI1-to-partner and partner-to-MEI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORA1B grouped by MEI1-low versus MEI1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEI1→partner) and Y-score (partner→MEI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNORA1B →	+0.519	+2.635	<.001	.006	3	3
CESC	ALDH7A1P2 →	+0.049	+4.539	.004	.008	3	3
UCEC	C14orf119 →	+0.232	+3.787	.007	<.001	3	3
UCEC	CDCA2 →	+0.773	+2.524	<.001	<.001	3	3
COAD	ADAMTSL2 →	-0.829	-3.399	.002	.005	3	3
UCEC	ABHD17AP1 →	+0.310	+1.436	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,995 associations by consensus.

SNORA1B by MEI1 expression — COAD

Explore this box plot interactively →