MEGF9

Across TCGA patient cohorts, MEGF9 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,023 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MEGF9-associated proteins across cancer lineages are PDIA4, SPATA20, and PTGR1. Each is linked with MEGF9 in more than 5 cancer types. Because this analysis shows association rather than direction, both MEGF9-to-partner and partner-to-MEGF9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEGF9 versus PDIA4 in CCRCC, with a Pearson correlation of -0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MEGF9→partner) and Y-score (partner→MEGF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PDIA4 →	-0.419	-0.391	<.001	.002	3	5
BRCA	SPATA20 →	+0.586	+0.949	<.001	<.001	3	5
LSCC	PTGR1 →	+1.192	+1.215	<.001	<.001	3	5
LSCC	RELB →	-0.349	-0.904	<.001	<.001	3	5
LUAD	AK1 →	+0.575	+0.516	<.001	.001	3	5
HNSC	EPS8 →	+0.614	+0.811	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,023 associations by consensus.

MEGF9 vs PDIA4 — CCRCC

Explore this scatter interactively →