MEF2D

Across TCGA cell cohorts, MEF2D mutation is significantly associated with the mutation status of many other genes, with 2,363 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MEF2D-associated genes across cancer lineages are LIMCH1, CNTNAP1, and SCARF1. Each is linked with MEF2D in more than 4 cancer types. Because this analysis shows association rather than direction, both MEF2D-to-partner and partner-to-MEF2D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LIMCH1 grouped by MEF2D-low versus MEF2D-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEF2D→partner) and Y-score (partner→MEF2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LIMCH1 →	+2.367	+3.372	.002	.002	1	5
SKIN	CNTNAP1 →	+3.357	+3.532	.005	.005	1	4
OVARY	SCARF1 →	+4.977	+4.415	.007	.007	1	4
BLOOD_Leukemia	USP35 →	+3.020	+4.545	.004	.004	1	4
BLOOD_Leukemia	ZNF600 →	+4.309	+4.560	.007	.007	1	4
OVARY	ONECUT2 →	+4.977	+4.415	.007	.007	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,363 associations by consensus.

LIMCH1 by MEF2D expression — LARGE_INTESTINE

Explore this box plot interactively →