MEF2A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MEF2A protein abundance is significantly associated with the RNA expression of many other genes, with 5,177 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MEF2A-associated genes across cancer lineages are A2M, GYPC, and FGF2. Each is linked with MEF2A in more than 3 cancer types. Because this analysis shows association rather than direction, both MEF2A-to-partner and partner-to-MEF2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEF2A versus A2M in CCRCC, with a Pearson correlation of 0.63.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEF2A→partner) and Y-score (partner→MEF2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCA2M →+1.101+0.544<.001.00434
CCRCCGYPC →+0.938+0.528<.001.00133
PDACFGF2 →+1.168+0.506<.001.00133
PDACABI3BP →+0.880+0.358.004.00333
HNSCCA3 →+1.164+0.188<.001.00133
CCRCCF8 →+0.921+0.438.006.00933
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,177 associations by consensus.

MEF2A vs A2M — CCRCC

Per-sample scatter of MEF2A vs A2M in CCRCC (Pearson r = 0.63).

Explore this scatter interactively →

Exploration