MEF2A

Across TCGA cell cohorts, MEF2A mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MEF2A-associated genes across cancer lineages are GSTA2, CCDC195, and OPN1MW2. Each is linked with MEF2A in more than 1 cancer types. Because this analysis shows association rather than direction, both MEF2A-to-partner and partner-to-MEF2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSTA2 grouped by MEF2A-low versus MEF2A-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MEF2A→partner) and Y-score (partner→MEF2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	GSTA2 →	+0.010	+3.906	.007	.009	3	1
BLOOD_Myeloma	CCDC195 →	+0.069	+4.285	<.001	.003	3	1
URINARY_TRACT	OPN1MW2 →	+0.020	+5.087	<.001	.004	3	1
LARGE_INTESTINE	C1QTNF7 →	+0.154	+4.108	<.001	.008	3	1
LARGE_INTESTINE	GYPA →	+0.110	+3.793	<.001	.007	3	1
LARGE_INTESTINE	GSG1L2 →	+0.016	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

GSTA2 by MEF2A expression — BLOOD_Myeloma

Explore this box plot interactively →