MED9

Across TCGA cell cohorts, MED9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,620 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MED9-associated GO terms across cancer lineages are Negative regulation of brown fat cell differentiation, Positive regulation of transcription elongation by RNA polymerase II, and Regulation of transcription initiation by RNA polymerase II. Each is linked with MED9 in more than 15 cancer types. Because this analysis shows association rather than direction, both MED9-to-partner and partner-to-MED9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of brown fat cell differentiation grouped by MED9-low versus MED9-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MED9→partner) and Y-score (partner→MED9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of brown fat cell differentiation →	+0.187	+0.723	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Positive regulation of transcription elongation by RNA polymerase II →	+0.075	+0.667	<.001	<.001	3	15
LARGE_INTESTINE	Regulation of transcription initiation by RNA polymerase II →	+0.069	+0.695	<.001	<.001	3	15
BREAST	Positive regulation of transcription initiation by RNA polymerase II →	+0.082	+0.906	<.001	<.001	3	15
OESOPHAGUS	Transcription preinitiation complex assembly →	+0.077	+0.902	.003	.003	2	16
LUNG_NSCLC_LUSC	DNA topological change →	+0.176	+0.977	<.001	.006	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,620 associations by consensus.

Negative regulation of brown fat cell differentiation by MED9 expression — STOMACH

Explore this box plot interactively →