MED6

Across TCGA patient cohorts, MED6 protein abundance is significantly associated with the RNA expression of many other genes, with 15,044 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED6-associated genes across cancer lineages are VRK1, SASS6, and KNTC1. Each is linked with MED6 in more than 6 cancer types. Because this analysis shows association rather than direction, both MED6-to-partner and partner-to-MED6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED6 versus VRK1 in LSCC, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MED6→partner) and Y-score (partner→MED6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VRK1 →	+0.716	+0.274	<.001	<.001	3	7
GBM	SASS6 →	+0.601	+0.404	<.001	<.001	3	7
GBM	KNTC1 →	+0.749	+0.397	<.001	<.001	3	7
GBM	LUC7L3 →	+0.420	+0.327	<.001	<.001	3	6
LSCC	RAD51C →	+0.474	+0.233	<.001	<.001	3	6
GBM	FOXM1 →	+1.060	+0.356	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,044 associations by consensus.

MED6 vs VRK1 — LSCC

Explore this scatter interactively →