MED29

Across TCGA patient cohorts, MED29 mutation is significantly associated with the RNA expression of many other genes, with 103 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MED29-associated genes across cancer lineages are RN7SKP96, IGKV2-14, and LINC01975. Each is linked with MED29 in more than 1 cancer types. Because this analysis shows association rather than direction, both MED29-to-partner and partner-to-MED29 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP96 grouped by MED29-low versus MED29-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MED29→partner) and Y-score (partner→MED29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RN7SKP96 →	+0.140	+4.039	<.001	.001	3	2
HNSC	IGKV2-14 →	+0.161	+4.864	<.001	<.001	3	2
UCEC	LINC01975 →	+0.446	+3.293	<.001	.001	3	1
UCEC	RN7SL147P →	+0.223	+3.135	.001	.002	3	1
UCEC	ATP6V1E1P2 →	+0.172	+2.755	.007	.009	3	1
UCEC	WBP1LP6 →	+0.112	+4.437	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 103 associations by consensus.

RN7SKP96 by MED29 expression — HNSC

Explore this box plot interactively →