MED28

Across TCGA cell cohorts, MED28 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,553 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MED28-associated GO terms across cancer lineages are DAMP biosynthetic process, Purine deoxyribonucleoside monophosphate biosynthetic process, and Cell cycle phase transition. Each is linked with MED28 in more than 10 cancer types. Because this analysis shows association rather than direction, both MED28-to-partner and partner-to-MED28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DAMP biosynthetic process grouped by MED28-low versus MED28-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MED28→partner) and Y-score (partner→MED28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DAMP biosynthetic process →	+0.138	+0.937	.001	<.001	3	11
PANCREAS	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.138	+0.937	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Cell cycle phase transition →	+0.062	+0.945	.004	.009	3	11
BLOOD_Leukemia	mRNA alternative polyadenylation →	+0.057	+0.873	<.001	<.001	3	10
BLOOD_Lymphoma	Transcription pausing by RNA polymerase II →	+0.127	+1.227	<.001	<.001	3	10
LARGE_INTESTINE	Mitotic cell cycle phase transition →	+0.039	+0.543	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,553 associations by consensus.

DAMP biosynthetic process by MED28 expression — PANCREAS

Explore this box plot interactively →