MED27

Across TCGA patient cohorts, MED27 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,165 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED27-associated proteins across cancer lineages are PRRC2B, GTF3C4, and EHMT1. Each is linked with MED27 in more than 6 cancer types. Because this analysis shows association rather than direction, both MED27-to-partner and partner-to-MED27 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED27 versus PRRC2B in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MED27→partner) and Y-score (partner→MED27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PRRC2B →	+0.323	+0.365	<.001	<.001	3	7
LSCC	GTF3C4 →	+0.392	+0.492	<.001	<.001	3	7
COAD	EHMT1 →	+0.386	+0.500	<.001	<.001	3	6
OV	FUBP3 →	+0.237	+0.530	.002	.003	3	6
GBM	SMC2 →	+0.485	+0.233	<.001	<.001	3	6
GBM	BRD3 →	+0.359	+0.304	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,165 associations by consensus.

MED27 vs PRRC2B — LSCC

Explore this scatter interactively →