MED27

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MED27 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MED27-associated genes across cancer lineages are PTH2R. Each is linked with MED27 in more than 1 cancer types. Because this analysis shows association rather than direction, both MED27-to-partner and partner-to-MED27 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTH2R grouped by MED27-low versus MED27-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MED27→partner) and Y-score (partner→MED27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEPTH2R →+0.655+3.453.008.00911
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

PTH2R by MED27 expression — LARGE_INTESTINE

Box plot of PTH2R in MED27-low vs MED27-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration