MED25

Across TCGA patient cohorts, MED25 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,874 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MED25-associated proteins across cancer lineages are TRIM28, SYTL1, and SF3B3. Each is linked with MED25 in more than 5 cancer types. Because this analysis shows association rather than direction, both MED25-to-partner and partner-to-MED25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED25 versus TRIM28 in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MED25→partner) and Y-score (partner→MED25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.312	+0.379	<.001	<.001	3	6
CCRCC	SYTL1 →	-0.595	-0.238	<.001	.009	3	4
COAD	SF3B3 →	+0.196	+0.937	<.001	<.001	3	4
GBM	KHDRBS1 →	+0.252	+0.431	.001	<.001	3	4
GBM	DHX9 →	+0.212	+0.375	<.001	<.001	3	4
GBM	PAFAH1B3 →	+0.288	+0.315	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,874 associations by consensus.

MED25 vs TRIM28 — GBM

Explore this scatter interactively →