MED19

Across TCGA patient cohorts, MED19 protein abundance is significantly associated with the RNA expression of many other genes, with 12,664 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED19-associated genes across cancer lineages are PODN, NOL11, and MAGOH. Each is linked with MED19 in more than 4 cancer types. Because this analysis shows association rather than direction, both MED19-to-partner and partner-to-MED19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED19 versus PODN in OV, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MED19→partner) and Y-score (partner→MED19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PODN →	-1.233	-0.401	.001	<.001	3	5
LSCC	NOL11 →	+0.728	+0.265	<.001	<.001	3	5
BRCA	MAGOH →	+0.738	+0.307	<.001	<.001	3	5
LSCC	GINS1 →	+0.867	+0.277	<.001	<.001	3	4
LSCC	KIF14 →	+0.783	+0.257	<.001	<.001	3	4
LSCC	HELLS →	+0.886	+0.211	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,664 associations by consensus.

MED19 vs PODN — OV

Explore this scatter interactively →