MED17

Across TCGA patient cohorts, MED17 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,822 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MED17-associated proteins across cancer lineages are MRE11, RSF1, and CUL5. Each is linked with MED17 in more than 6 cancer types. Because this analysis shows association rather than direction, both MED17-to-partner and partner-to-MED17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED17 versus MRE11 in GBM, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MED17→partner) and Y-score (partner→MED17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MRE11 →	+0.372	+0.382	<.001	<.001	3	7
GBM	RSF1 →	+0.327	+0.265	<.001	<.001	3	6
HNSC	CUL5 →	+0.202	+0.424	<.001	<.001	3	5
GBM	CPSF7 →	+0.294	+0.294	<.001	<.001	3	5
LSCC	CWF19L2 →	+0.312	+0.382	<.001	<.001	3	5
HNSC	FAM76B →	+0.350	+0.312	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,822 associations by consensus.

MED17 vs MRE11 — GBM

Explore this scatter interactively →