MED15

Across TCGA cell cohorts, MED15 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,911 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MED15-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Caveolin-mediated endocytosis. Each is linked with MED15 in more than 16 cancer types. Because this analysis shows association rather than direction, both MED15-to-partner and partner-to-MED15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by MED15-low versus MED15-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MED15→partner) and Y-score (partner→MED15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Symbiont-mediated disruption of host cellular anatomical structure →	+0.138	+1.244	<.001	<.001	3	17
URINARY_TRACT	Symbiont-mediated disruption of host anatomical structure →	+0.138	+1.244	<.001	<.001	3	17
LIVER	Caveolin-mediated endocytosis →	+0.211	+1.322	.001	.003	3	16
URINARY_TRACT	Regulation of Golgi inheritance →	+0.188	+1.167	<.001	<.001	3	16
BONE	Positive regulation of plasma membrane repair →	+0.260	+0.785	<.001	<.001	3	16
LARGE_INTESTINE	Caveola assembly →	+0.244	+0.914	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,911 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by MED15 expression — URINARY_TRACT

Explore this box plot interactively →