MED14OS

Across TCGA patient cohorts, MED14OS RNA expression is significantly associated with the go_rna of many other GO terms, with 7,139 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MED14OS-associated GO terms across cancer lineages are B cell activation involved in immune response, Stress-activated protein kinase signaling cascade, and Positive regulation of canonical NF-kappaB signal transduction. Each is linked with MED14OS in more than 21 cancer types. Because this analysis shows association rather than direction, both MED14OS-to-partner and partner-to-MED14OS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell activation involved in immune response grouped by MED14OS-low versus MED14OS-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MED14OS→partner) and Y-score (partner→MED14OS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	B cell activation involved in immune response →	+0.032	+0.427	<.001	<.001	3	22
UVM	Stress-activated protein kinase signaling cascade →	+0.031	+0.503	<.001	<.001	3	21
UVM	Positive regulation of canonical NF-kappaB signal transduction →	+0.036	+0.566	<.001	<.001	3	21
UVM	Obsolete regulation of dosage compensation by inactivation of X chromosome →	+0.073	+0.606	<.001	<.001	3	20
UVM	Myeloid cell homeostasis →	+0.040	+0.556	<.001	<.001	3	20
UVM	Cytoplasmic pattern recognition receptor signaling pathway →	+0.031	+0.495	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,139 associations by consensus.

B cell activation involved in immune response by MED14OS expression — TGCT

Explore this box plot interactively →