MED13

Across TCGA patient cohorts, MED13 protein abundance is significantly associated with the RNA expression of many other genes, with 12,843 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED13-associated genes across cancer lineages are MRPL4, SLC25A19, and BRIP1. Each is linked with MED13 in more than 3 cancer types. Because this analysis shows association rather than direction, both MED13-to-partner and partner-to-MED13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED13 versus MRPL4 in BRCA, with a Pearson correlation of 0.24.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MED13→partner) and Y-score (partner→MED13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MRPL4 →	+0.621	+0.293	<.001	<.001	3	4
BRCA	SLC25A19 →	+0.470	+0.257	<.001	<.001	3	4
LSCC	BRIP1 →	+0.755	+0.211	<.001	<.001	3	4
BRCA	PTRH2 →	+0.644	+0.337	<.001	<.001	3	4
UCEC	EME1 →	+0.889	+0.291	.001	<.001	3	4
UCEC	SAP30BP →	+0.703	+0.234	.001	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,843 associations by consensus.

MED13 vs MRPL4 — BRCA

Explore this scatter interactively →