MED13

Across TCGA cell cohorts, MED13 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,882 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MED13-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Negative regulation of gene expression, epigenetic, and Protein modification by small protein removal. Each is linked with MED13 in more than 17 cancer types. Because this analysis shows association rather than direction, both MED13-to-partner and partner-to-MED13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by MED13-low versus MED13-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MED13→partner) and Y-score (partner→MED13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Epigenetic regulation of gene expression →	+0.070	+0.817	<.001	<.001	3	18
BONE	Negative regulation of gene expression, epigenetic →	+0.078	+0.726	.001	<.001	3	18
SOFT_TISSUE	Protein modification by small protein removal →	+0.061	+0.838	<.001	<.001	3	17
BONE	Heterochromatin organization →	+0.077	+0.763	.004	<.001	3	17
SOFT_TISSUE	Heterochromatin formation →	+0.079	+0.892	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of beige fat cell differentiation →	+0.128	+0.972	<.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,882 associations by consensus.

Epigenetic regulation of gene expression by MED13 expression — SOFT_TISSUE

Explore this box plot interactively →