MED12L

Across TCGA patient cohorts, MED12L RNA expression is significantly associated with the protein abundance of many other proteins, with 17,043 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED12L-associated proteins across cancer lineages are ERO1A, UBR7, and ZNF609_S491. Each is linked with MED12L in more than 4 cancer types. Because this analysis shows association rather than direction, both MED12L-to-partner and partner-to-MED12L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MED12L versus ERO1A in GBM, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MED12L→partner) and Y-score (partner→MED12L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ERO1A →	-0.503	-0.651	.001	<.001	3	5
LSCC	UBR7 →	+0.359	+0.826	<.001	<.001	3	5
HNSC	ZNF609_S491 →	+0.288	+0.525	.007	.003	3	4
HNSC	RFX5 →	+0.404	+0.738	<.001	<.001	3	4
BRCA	S100A8 →	-1.214	-0.361	<.001	.001	3	4
BRCA	S100A9 →	-1.184	-0.478	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,043 associations by consensus.

MED12L vs ERO1A — GBM

Explore this scatter interactively →