Across TCGA patient cohorts, MED12 protein abundance is significantly associated with the RNA expression of many other genes, with 14,207 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MED12-associated genes across cancer lineages are PSMG4, MTARC1, and UNK. Each is linked with MED12 in more than 4 cancer types. Because this analysis shows association rather than direction, both MED12-to-partner and partner-to-MED12 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MED12→partner) and Y-score (partner→MED12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PSMG4 →	+0.473	+0.332	.003	<.001	3	5
LUAD	MTARC1 →	+0.784	+0.136	.001	.003	3	5
HNSC	UNK →	+0.514	+0.135	.003	.006	3	5
LSCC	CCDC38 →	+0.512	+0.332	<.001	<.001	3	5
HNSC	C12orf73 →	+0.589	+0.221	<.001	<.001	3	5
HNSC	PXN-AS1 →	+0.433	+0.204	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,207 associations by consensus.

Exploration

MED12 survival (RNA) · tumor vs normal (RNA) · all MED12 data types