MECOM-AS1

Across TCGA patient cohorts, MECOM-AS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,129 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MECOM-AS1-associated proteins across cancer lineages are MECOM_S726, MECOM, and MECOM_S624. Each is linked with MECOM-AS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both MECOM-AS1-to-partner and partner-to-MECOM-AS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MECOM-AS1 versus MECOM_S726 in LUAD, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MECOM-AS1→partner) and Y-score (partner→MECOM-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MECOM_S726 →	+1.028	+1.580	<.001	<.001	3	7
HNSC	MECOM →	+0.783	+1.494	<.001	<.001	3	6
LUAD	MECOM_S624 →	+1.324	+1.626	<.001	<.001	3	6
PDAC	MECOM_S1064 →	+1.023	+1.282	<.001	<.001	3	4
HNSC	PHC3 →	+0.391	+1.193	<.001	<.001	3	4
BRCA	RRP1B →	-0.276	-0.200	.003	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,129 associations by consensus.

MECOM-AS1 vs MECOM_S726 — LUAD

Explore this scatter interactively →