MEA1

Across TCGA patient cohorts, MEA1 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,437 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible MEA1-associated proteins across cancer lineages are HSP90AB1, TXNDC17, and PFDN5. Each is linked with MEA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MEA1-to-partner and partner-to-MEA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MEA1 versus HSP90AB1 in BRCA, with a Pearson correlation of 0.39.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MEA1→partner) and Y-score (partner→MEA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HSP90AB1 →	+0.373	+0.397	<.001	<.001	3	6
LUAD	TXNDC17 →	+0.485	+0.305	<.001	<.001	3	5
OV	PFDN5 →	+0.263	+0.378	<.001	<.001	3	5
UCEC	EIF4A1 →	+0.281	+0.376	<.001	.001	2	6
HNSC	NACA →	+0.606	+0.280	.004	.003	3	5
UCEC	NPNT →	-0.637	-0.302	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,437 associations by consensus.

MEA1 vs HSP90AB1 — BRCA

Explore this scatter interactively →