MEA1

Across TCGA cell cohorts, MEA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,536 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MEA1-associated GO terms across cancer lineages are Protein peptidyl-prolyl isomerization, Trophectodermal cell differentiation, and Regulation of nuclear division. Each is linked with MEA1 in more than 10 cancer types. Because this analysis shows association rather than direction, both MEA1-to-partner and partner-to-MEA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein peptidyl-prolyl isomerization grouped by MEA1-low versus MEA1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MEA1→partner) and Y-score (partner→MEA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein peptidyl-prolyl isomerization →	+0.129	+0.905	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Trophectodermal cell differentiation →	+0.148	+0.716	.002	.002	3	10
PANCREAS	Regulation of nuclear division →	+0.090	+0.729	<.001	<.001	3	10
OVARY	Double-strand break repair via break-induced replication →	+0.134	+0.561	.005	.003	3	10
PANCREAS	Negative regulation of metaphase/anaphase transition of cell cycle →	+0.148	+0.930	<.001	<.001	3	10
PANCREAS	Negative regulation of chromosome separation →	+0.148	+0.930	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,536 associations by consensus.

Protein peptidyl-prolyl isomerization by MEA1 expression — PANCREAS

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