ME3

Across TCGA patient cohorts, ME3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,886 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ME3-associated proteins across cancer lineages are CRYZL1, UTRN, and RRBP1_S615. Each is linked with ME3 in more than 4 cancer types. Because this analysis shows association rather than direction, both ME3-to-partner and partner-to-ME3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ME3 versus CRYZL1 in PDAC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ME3→partner) and Y-score (partner→ME3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	CRYZL1 →	+0.345	+0.276	.005	.001	3	5
HNSC	UTRN →	+0.242	+0.613	<.001	<.001	3	4
BRCA	RRBP1_S615 →	-0.799	-0.978	<.001	<.001	3	4
BRCA	TNS2 →	+0.369	+1.245	<.001	<.001	3	4
BRCA	TNS2_S102 →	+0.730	+1.001	<.001	<.001	3	4
LSCC	TNS2_S648 →	+0.646	+0.906	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,886 associations by consensus.

ME3 vs CRYZL1 — PDAC

Explore this scatter interactively →