ME1

Across TCGA cell cohorts, ME1 RNA expression is significantly associated with the RNA expression of many other genes, with 8,061 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ME1-associated genes across cancer lineages are AKR1B10, PRDX1, and PGD. Each is linked with ME1 in more than 7 cancer types. Because this analysis shows association rather than direction, both ME1-to-partner and partner-to-ME1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ME1 versus AKR1B10 in OESOPHAGUS, with a Pearson correlation of 0.53.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ME1→partner) and Y-score (partner→ME1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	AKR1B10 →	+3.815	+1.269	<.001	.003	3	8
LUNG_NSCLC_LUSC	PRDX1 →	+1.330	+2.377	<.001	<.001	3	7
LUNG_NSCLC_LUSC	PGD →	+2.385	+2.288	<.001	<.001	3	7
LUNG_NSCLC_LUSC	AKR1C2 →	+7.479	+2.560	<.001	<.001	3	7
LUNG_NSCLC_LUSC	AKR1C3 →	+6.078	+2.465	<.001	<.001	3	7
BONE	ANXA7 →	+0.771	+1.511	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,061 associations by consensus.

ME1 vs AKR1B10 — OESOPHAGUS

Explore this scatter interactively →