MDH1B

Across TCGA cell cohorts, MDH1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,913 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MDH1B-associated GO terms across cancer lineages are Intraciliary anterograde transport, Protein localization to cilium, and Microtubule-based transport. Each is linked with MDH1B in more than 16 cancer types. Because this analysis shows association rather than direction, both MDH1B-to-partner and partner-to-MDH1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary anterograde transport grouped by MDH1B-low versus MDH1B-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MDH1B→partner) and Y-score (partner→MDH1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Intraciliary anterograde transport →	+0.088	+0.790	<.001	.001	3	17
LIVER	Protein localization to cilium →	+0.080	+1.014	.005	.003	3	17
LUNG_SCLC	Microtubule-based transport →	+0.067	+0.878	<.001	<.001	3	16
SOFT_TISSUE	Intraciliary transport →	+0.061	+0.856	<.001	<.001	3	15
LUNG_SCLC	Transport along microtubule →	+0.071	+0.755	<.001	<.001	3	15
LUNG_SCLC	Cytoskeleton-dependent intracellular transport →	+0.068	+0.820	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,913 associations by consensus.

Intraciliary anterograde transport by MDH1B expression — PANCREAS

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