MDFIC2

Across TCGA patient cohorts, MDFIC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,790 significant associations in total. STAD shows the largest number of these associations.

The most reproducible MDFIC2-associated GO terms across cancer lineages are Mitochondrial respiratory chain complex assembly, Obsolete DNA methylation, and Aerobic respiration. Each is linked with MDFIC2 in more than 7 cancer types. Because this analysis shows association rather than direction, both MDFIC2-to-partner and partner-to-MDFIC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial respiratory chain complex assembly grouped by MDFIC2-low versus MDFIC2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MDFIC2→partner) and Y-score (partner→MDFIC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Mitochondrial respiratory chain complex assembly →	+0.104	+0.077	<.001	<.001	3	8
STAD	Obsolete DNA methylation →	+0.081	+0.067	<.001	<.001	3	7
STAD	Aerobic respiration →	+0.107	+0.073	<.001	<.001	3	7
STAD	Establishment of protein localization to membrane →	+0.086	+0.061	<.001	<.001	3	7
STAD	Positive regulation of mitotic cell cycle →	+0.078	+0.063	<.001	<.001	3	7
STAD	Regulation of DNA-templated DNA replication →	+0.087	+0.051	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,790 associations by consensus.

Mitochondrial respiratory chain complex assembly by MDFIC2 expression — STAD

Explore this box plot interactively →