MDFIC2

Across TCGA cell cohorts, MDFIC2 RNA expression is significantly associated with the mutation status of many other genes, with 103 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MDFIC2-associated genes across cancer lineages are NTNG2, PRRC2A, and MEGF11. Each is linked with MDFIC2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MDFIC2-to-partner and partner-to-MDFIC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NTNG2 grouped by MDFIC2-low versus MDFIC2-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MDFIC2→partner) and Y-score (partner→MDFIC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	NTNG2 →	+4.930	+0.228	.008	<.001	3	2
LUNG_NSCLC_LUSC	PRRC2A →	+4.643	+0.026	.008	<.001	3	2
SKIN	MEGF11 →	+2.977	+0.055	.006	.002	3	2
SOFT_TISSUE	PTPRJ →	+4.930	+0.276	.008	<.001	3	1
SOFT_TISSUE	RDH13 →	+4.930	+0.228	.008	<.001	3	1
SOFT_TISSUE	FAM71A →	+4.930	+0.266	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 103 associations by consensus.

NTNG2 by MDFIC2 expression — SOFT_TISSUE

Explore this box plot interactively →