MCUB

Across TCGA pan-cancer cohorts, MCUB Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated MCUB data layer compared with 25 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MCUB Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated MCUB expression acts as an unfavorable survival marker.

LUAD, SKCM, and SCLC are the cancer types where MCUB Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.150	0.788	<.001	22	view →
SKCM	DFS	Median	All	0.231	0.624	<.001	20	view →
SCLC	DFS	Median	II,III,IV	0.137	0.562	.013	12	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

MCUB–LUAD (OS)

Open the LUAD breakdown →