MCUB

Across TCGA cell cohorts, MCUB RNA expression is significantly associated with the go_rna of many other GO terms, with 4,399 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MCUB-associated GO terms across cancer lineages are Negative regulation of mitotic nuclear division, Positive regulation of skeletal muscle cell differentiation, and Negative regulation of nuclear division. Each is linked with MCUB in more than 12 cancer types. Because this analysis shows association rather than direction, both MCUB-to-partner and partner-to-MCUB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of mitotic nuclear division grouped by MCUB-low versus MCUB-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCUB→partner) and Y-score (partner→MCUB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of mitotic nuclear division →	+0.152	+0.890	.001	.004	3	13
BREAST	Positive regulation of skeletal muscle cell differentiation →	+0.236	+1.329	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of nuclear division →	+0.087	+0.630	.002	.008	3	11
URINARY_TRACT	CMP biosynthetic process →	+0.140	+1.343	.002	.003	2	12
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome segregation →	+0.116	+0.807	.003	.001	2	11
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic sister chromatid separation →	+0.155	+1.037	.002	.004	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,399 associations by consensus.

Negative regulation of mitotic nuclear division by MCUB expression — OESOPHAGUS

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