MCTP2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MCTP2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,266 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MCTP2-associated genes across cancer lineages are DIPK1B, FGF14, and ZC3H13. Each is linked with MCTP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both MCTP2-to-partner and partner-to-MCTP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCTP2 versus DIPK1B in OV, with a Pearson correlation of -0.53.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCTP2→partner) and Y-score (partner→MCTP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVDIPK1B →-1.055-0.630.004<.00133
LSCCFGF14 →-0.546-0.353.001.00133
COADZC3H13 →-0.553-0.607.001<.00133
COADSETDB1 →-0.379-0.412<.001.00133
LUADCLIP3 →-0.475-0.323<.001.00133
LSCCKLF12 →-0.866-0.453<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,266 associations by consensus.

MCTP2 vs DIPK1B — OV

Per-sample scatter of MCTP2 vs DIPK1B in OV (Pearson r = -0.53).

Explore this scatter interactively →

Exploration