Across TCGA patient cohorts, MCRS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,876 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MCRS1-associated proteins across cancer lineages are SCAF11, MYG1, and EIF4B. Each is linked with MCRS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both MCRS1-to-partner and partner-to-MCRS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MCRS1→partner) and Y-score (partner→MCRS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SCAF11 →	+0.384	+0.520	.001	.001	3	6
LSCC	MYG1 →	+0.290	+0.532	<.001	<.001	3	6
OV	EIF4B →	+0.327	+0.451	.001	.004	3	6
OV	PTGES3 →	+0.393	+0.452	.005	.001	3	5
GBM	PBRM1 →	+0.299	+0.250	<.001	.001	3	5
OV	ARID2 →	+0.283	+0.538	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,876 associations by consensus.

Exploration

MCRS1 survival (RNA) · tumor vs normal (RNA) · all MCRS1 data types