MCOLN3

Across TCGA patient cohorts, MCOLN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,057 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MCOLN3-associated proteins across cancer lineages are MAP1B_S1625, AP3B2_S272, and COPB1. Each is linked with MCOLN3 in more than 3 cancer types. Because this analysis shows association rather than direction, both MCOLN3-to-partner and partner-to-MCOLN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCOLN3 versus MAP1B_S1625 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MCOLN3→partner) and Y-score (partner→MCOLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MAP1B_S1625 →	+0.848	+0.894	<.001	<.001	3	4
BRCA	AP3B2_S272 →	+1.632	+0.884	.001	.004	3	4
BRCA	COPB1 →	-0.243	-1.027	<.001	<.001	3	4
LSCC	GNL1 →	+0.192	+0.564	<.001	.001	3	4
LSCC	TSPAN1 →	-1.020	-1.040	<.001	<.001	3	4
LUAD	TC2N →	-0.849	-0.852	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,057 associations by consensus.

MCOLN3 vs MAP1B_S1625 — LSCC

Explore this scatter interactively →