MCOLN3

Across TCGA cell cohorts, MCOLN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,369 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible MCOLN3-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, Protein-DNA complex organization, and RNA splicing, via transesterification reactions. Each is linked with MCOLN3 in more than 11 cancer types. Because this analysis shows association rather than direction, both MCOLN3-to-partner and partner-to-MCOLN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of syncytium formation by plasma membrane fusion grouped by MCOLN3-low versus MCOLN3-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCOLN3→partner) and Y-score (partner→MCOLN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.116	+2.119	<.001	<.001	3	12
OESOPHAGUS	Protein-DNA complex organization →	+0.074	+2.000	.004	.001	3	11
SOFT_TISSUE	RNA splicing, via transesterification reactions →	+0.074	+1.426	<.001	.001	3	11
OESOPHAGUS	Cytoplasmic translation →	+0.115	+2.563	.005	<.001	3	11
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.158	+2.316	.003	<.001	2	11
PANCREAS	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.068	+1.698	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,369 associations by consensus.

Regulation of syncytium formation by plasma membrane fusion by MCOLN3 expression — STOMACH

Explore this box plot interactively →