MCOLN2

Across TCGA patient cohorts, MCOLN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,839 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MCOLN2-associated proteins across cancer lineages are SEPTIN1_S206, TNFAIP8, and PSMB10. Each is linked with MCOLN2 in more than 8 cancer types. Because this analysis shows association rather than direction, both MCOLN2-to-partner and partner-to-MCOLN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCOLN2 versus SEPTIN1_S206 in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MCOLN2→partner) and Y-score (partner→MCOLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SEPTIN1_S206 →	+0.948	+0.696	<.001	.001	3	9
GBM	TNFAIP8 →	+0.873	+0.922	<.001	<.001	3	9
HNSC	PSMB10 →	+0.586	+1.009	<.001	<.001	3	8
HNSC	PTPN7 →	+0.528	+1.100	<.001	<.001	3	8
UCEC	RAC2 →	+0.609	+1.103	<.001	<.001	3	8
HNSC	RASAL3 →	+0.474	+1.043	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,839 associations by consensus.

MCOLN2 vs SEPTIN1_S206 — HNSC

Explore this scatter interactively →