MCOLN2

Across TCGA cell cohorts, MCOLN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,848 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MCOLN2-associated GO terms across cancer lineages are 'de novo' IMP biosynthetic process, Transcription by RNA polymerase I, and Maturation of SSU-rRNA. Each is linked with MCOLN2 in more than 9 cancer types. Because this analysis shows association rather than direction, both MCOLN2-to-partner and partner-to-MCOLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' IMP biosynthetic process grouped by MCOLN2-low versus MCOLN2-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCOLN2→partner) and Y-score (partner→MCOLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	'de novo' IMP biosynthetic process →	+0.112	+1.426	<.001	.003	3	10
PANCREAS	Transcription by RNA polymerase I →	+0.084	+1.225	<.001	<.001	3	8
BLOOD_Lymphoma	Maturation of SSU-rRNA →	+0.093	+1.383	<.001	.004	2	9
PANCREAS	IMP biosynthetic process →	+0.162	+1.419	<.001	.001	3	8
LUNG_SCLC	Mitochondrial RNA modification →	+0.103	+1.574	<.001	.002	3	8
SKIN	Regulation of epithelial cell differentiation →	-0.045	-0.996	.005	.008	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,848 associations by consensus.

'de novo' IMP biosynthetic process by MCOLN2 expression — BLOOD_Lymphoma

Explore this box plot interactively →