MCMDC2

Across TCGA patient cohorts, MCMDC2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,504 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MCMDC2-associated proteins across cancer lineages are RBM12B, PRKDC, and TMOD3. Each is linked with MCMDC2 in more than 6 cancer types. Because this analysis shows association rather than direction, both MCMDC2-to-partner and partner-to-MCMDC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCMDC2 versus RBM12B in GBM, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MCMDC2→partner) and Y-score (partner→MCMDC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBM12B →	+0.311	+0.411	<.001	<.001	3	7
COAD	PRKDC →	+0.355	+0.761	<.001	<.001	3	6
GBM	TMOD3 →	-0.248	-0.315	<.001	<.001	3	5
BRCA	PPIB →	-0.351	-0.479	<.001	.001	3	5
HNSC	ZNF638 →	+0.269	+0.543	<.001	<.001	3	5
LUAD	DKC1 →	+0.317	+0.667	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,504 associations by consensus.

MCMDC2 vs RBM12B — GBM

Explore this scatter interactively →