Across TCGA patient cohorts, MCMBP protein abundance is significantly associated with the RNA expression of many other genes, with 13,366 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MCMBP-associated genes across cancer lineages are SMC3, CCDC18, and HROB. Each is linked with MCMBP in more than 7 cancer types. Because this analysis shows association rather than direction, both MCMBP-to-partner and partner-to-MCMBP results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MCMBP→partner) and Y-score (partner→MCMBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SMC3 →	+0.581	+0.264	<.001	<.001	3	8
HNSC	CCDC18 →	+0.636	+0.277	<.001	<.001	3	8
LUAD	HROB →	+0.906	+0.214	<.001	<.001	3	8
BRCA	CEP55 →	+1.370	+0.414	<.001	<.001	3	8
COAD	KIF20B →	+0.897	+0.347	<.001	<.001	3	8
BRCA	CENPE →	+0.925	+0.326	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,366 associations by consensus.

Exploration

MCMBP survival (RNA) · tumor vs normal (RNA) · all MCMBP data types