MCM7

Across TCGA cell cohorts, MCM7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,684 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MCM7-associated GO terms across cancer lineages are DNA replication, DNA-templated DNA replication, and DNA replication initiation. Each is linked with MCM7 in more than 19 cancer types. Because this analysis shows association rather than direction, both MCM7-to-partner and partner-to-MCM7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication grouped by MCM7-low versus MCM7-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCM7→partner) and Y-score (partner→MCM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNA replication →	+0.119	+1.178	<.001	<.001	3	20
PANCREAS	DNA-templated DNA replication →	+0.129	+1.280	<.001	<.001	3	19
LUNG_NSCLC_LUSC	DNA replication initiation →	+0.221	+1.611	<.001	.001	3	19
SOFT_TISSUE	DNA strand elongation involved in DNA replication →	+0.185	+0.967	<.001	<.001	3	19
PANCREAS	Double-strand break repair via break-induced replication →	+0.209	+1.206	<.001	<.001	3	19
BONE	Meiotic chromosome condensation →	+0.236	+1.638	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,684 associations by consensus.

DNA replication by MCM7 expression — PANCREAS

Explore this box plot interactively →