MCM6

Across TCGA patient cohorts, MCM6 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,488 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MCM6-associated proteins across cancer lineages are FEN1, POLD1, and RIF1. Each is linked with MCM6 in more than 9 cancer types. Because this analysis shows association rather than direction, both MCM6-to-partner and partner-to-MCM6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCM6 versus FEN1 in OV, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MCM6→partner) and Y-score (partner→MCM6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FEN1 →	+0.542	+0.825	<.001	<.001	3	10
OV	POLD1 →	+0.381	+1.022	.001	<.001	3	10
LSCC	RIF1 →	+0.537	+0.752	<.001	<.001	3	10
LUAD	RRM2 →	+0.902	+0.882	<.001	<.001	3	10
GBM	SMC2 →	+0.681	+0.707	<.001	<.001	3	10
LUAD	SMC4 →	+0.652	+0.880	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,488 associations by consensus.

MCM6 vs FEN1 — OV

Explore this scatter interactively →