MCM3AP

Across TCGA cell cohorts, MCM3AP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,634 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MCM3AP-associated GO terms across cancer lineages are Microtubule nucleation, Epigenetic regulation of gene expression, and Viral translational termination-reinitiation. Each is linked with MCM3AP in more than 14 cancer types. Because this analysis shows association rather than direction, both MCM3AP-to-partner and partner-to-MCM3AP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule nucleation grouped by MCM3AP-low versus MCM3AP-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MCM3AP→partner) and Y-score (partner→MCM3AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Microtubule nucleation →	+0.139	+0.978	<.001	<.001	3	15
BONE	Epigenetic regulation of gene expression →	+0.067	+0.727	<.001	.002	3	15
OVARY	Viral translational termination-reinitiation →	+0.082	+0.980	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.079	+0.743	<.001	.004	3	14
OVARY	Regulation of double-strand break repair →	+0.063	+0.733	.001	.006	3	14
BREAST	Retrograde transport, endosome to Golgi →	+0.074	+0.915	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,634 associations by consensus.

Microtubule nucleation by MCM3AP expression — LARGE_INTESTINE

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