MCIDAS

Across TCGA patient cohorts, MCIDAS RNA expression is significantly associated with the protein abundance of many other proteins, with 12,071 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible MCIDAS-associated proteins across cancer lineages are RFC2, DDX47, and SUPT16H. Each is linked with MCIDAS in more than 4 cancer types. Because this analysis shows association rather than direction, both MCIDAS-to-partner and partner-to-MCIDAS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MCIDAS versus RFC2 in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MCIDAS→partner) and Y-score (partner→MCIDAS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RFC2 →	+0.439	+0.609	<.001	<.001	3	5
HNSC	DDX47 →	+0.298	+0.452	<.001	<.001	3	5
LSCC	SUPT16H →	+0.353	+0.707	.001	<.001	3	4
UCEC	SYDE1 →	-0.387	-0.863	.007	.006	3	4
LSCC	TFB2M →	+0.407	+0.591	<.001	.002	3	4
LSCC	NAT10 →	+0.282	+0.711	.003	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,071 associations by consensus.

MCIDAS vs RFC2 — HNSC

Explore this scatter interactively →