MCEMP1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MCEMP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MCEMP1 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher MCEMP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MCEMP1 expression acts as an unfavorable survival marker, although some lineages such as GBM and LSCC show a favorable association.

LUAD, UCEC, and GBM are the cancer types where MCEMP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSMedianAll0.8210.994.00816view →
UCECDFSTertileAll0.5721.000.01910view →
GBMDFSMedianAll0.6200.135.0362view →
LSCCOSQuartileAll0.9280.764.0422view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

MCEMP1–LUAD (DFS)

Kaplan–Meier survival curve for MCEMP1 mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration