MCEMP1

Across TCGA pan-cancer cohorts, MCEMP1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of MCEMP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where MCEMP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types MCEMP1 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

KIRC, COAD, and THCA are the cancer types where MCEMP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in MCEMP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	II,III,IV	+0.971	<.001	12	view →
COAD	All	IV	+1.697	<.001	11	view →
THCA	Male	II,III,IV	+2.113	<.001	10	view →
LUSC	Female	II,III,IV	−6.028	<.001	9	view →
LUAD	Female	III,IV	−4.817	<.001	9	view →
HNSC	Male	II,III,IV	+0.777	<.001	9	view →
STAD	Male	All	+0.683	<.001	4	view →
UCEC	All	All	+0.342	.031	4	view →
BRCA	All	II,III,IV	+0.266	<.001	4	view →
READ	All	III,IV	+1.475	.043	2	view →
ESCA	All	II,III,IV	+0.934	.016	2	view →
CHOL	All	All	+0.856	.005	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

MCEMP1–KIRC

Open the KIRC breakdown →